HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.

HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.

Human immunodeficiency virus type 1 encoded viral protein Vpr is essential for infection of macrophages by HIV-1. Furthermore, these macrophages are resistant to cell death and are viral reservoir. However, the impact of Vpr on the macrophage proteome is yet to be comprehended. The goal of the prese...

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Bibliographic Details
Main Authors: Carlos A Barrero, Prasun K Datta, Satarupa Sen, Satish Deshmane, Shohreh Amini, Kamel Khalili, Salim Merali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3709966?pdf=render

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