Polyphenols from Hippophae rhamnoides suppressed colon cancer growth by regulating miRNA-mediated cell cycle arrest and apoptosis in vitro and in vivo

Polyphenols from Hippophae rhamnoides suppressed colon cancer growth by regulating miRNA-mediated cell cycle arrest and apoptosis in vitro and in vivo

Colorectal cancer (CRC) is the most common gastrointestinal cancer. Hippophae rhamnoides are reported to possess a variety of active substances. MiRNAs are new therapeutic targets. Here, it found that Hippophae rhamnoides L. polyphenols (named as HPs60) exhibited significant anti-colon cancer activi...

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Bibliographic Details
Main Authors: Haili Wu, Chenglu Li, Mimi Cui, Huiqin Guo, Sen Chen, Jin'e Du, Hanqing Li, Zhuoyu Li
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Journal of Functional Foods
Subjects:
Hippophae Rhamnoide polyphenols
miRNAs
Cell cycle arrest
Apoptosis
Colon cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621004291

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