Favipiravir Does Not Inhibit Chikungunya Virus Replication in Mosquito Cells and <i>Aedes aegypti</i> Mosquitoes

Favipiravir Does Not Inhibit Chikungunya Virus Replication in Mosquito Cells and <i>Aedes aegypti</i> Mosquitoes

Favipiravir (T-705) is a broad-spectrum antiviral drug that inhibits RNA viruses after intracellular conversion into its active form, T-705 ribofuranosyl 5′-triphosphate. We previously showed that T-705 is able to significantly inhibit the replication of chikungunya virus (CHIKV), an arbovirus trans...

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Bibliographic Details
Main Authors: Sofie Jacobs, Lanjiao Wang, Ana Lucia Rosales Rosas, Ria Van Berwaer, Evelien Vanderlinden, Anna-Bella Failloux, Lieve Naesens, Leen Delang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Microorganisms
Subjects:
favipiravir
T-705
activation
antiviral activity
mosquitoes
chikungunya virus
Online Access:https://www.mdpi.com/2076-2607/9/5/944

Internet

https://www.mdpi.com/2076-2607/9/5/944

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