Structural prediction of RNA switches using conditional base-pair probabilities.

An RNA switch triggers biological functions by toggling between two conformations. RNA switches include bacterial riboswitches, where ligand binding can stabilize a bound structure. For RNAs with only one stable structure, structural prediction usually just requires a straightforward free energy min...

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Bibliographic Details
Main Authors: Amirhossein Manzourolajdad, John L Spouge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217625

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