Possible Protective Effect of Diacerein on Doxorubicin-Induced Nephrotoxicity in Rats

Possible Protective Effect of Diacerein on Doxorubicin-Induced Nephrotoxicity in Rats

Nephrotoxicity is one of the limiting factors for using doxorubicin (DOX). Interleukin 1 has major role in DOX-induced nephrotoxicity, so we investigated the effect of interleukin 1 receptor antagonist diacerein (DIA) on DOX-induced nephrotoxicity. DIA (25 and 50 mg/kg/day) was administered orally t...

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Bibliographic Details
Main Authors:	Marwa M. M. Refaie, Entesar F. Amin, Nashwa F. El-Tahawy, Aly M. Abdelrahman
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Journal of Toxicology
Online Access:	http://dx.doi.org/10.1155/2016/9507563

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