Specific and overlapping sphingosine-1-phosphate receptor functions in human synoviocytes: impact of TNF-α

Specific and overlapping sphingosine-1-phosphate receptor functions in human synoviocytes: impact of TNF-α

Sphingosine-1-phosphate (S1P), via interaction with its G protein-coupled receptors, regulates various physiological and pathological responses. The present study investigated the role of S1P/S1P receptor signaling in several functional responses of human fibroblast-like synoviocytes (FLSs) that may...

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Bibliographic Details
Main Authors: Chenqi Zhao, Maria J. Fernandes, Mélanie Turgeon, Sabrina Tancrède, John Di Battista, Patrice E. Poubelle, Sylvain G. Bourgoin
Format: Article
Language:English
Published: Elsevier 2008-11-01
Series:Journal of Lipid Research
Subjects:
inflammation
G protein-coupled receptor
interleukin-8
cell migration
apoptosis
mitogen-activated protein kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346101

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http://www.sciencedirect.com/science/article/pii/S0022227520346101

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