CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves
NAD+ and cognitive hypersensitivity during aging Cognitive dysfunction is one of the most concerning outcomes in global population aging. However, the mechanisms of cognitive impairment during aging remain elusive. We found that in old mice, levels of nicotinamide adenine dinucleotide (NAD+), an ess...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-11-01
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| Series: | npj Aging and Mechanisms of Disease |
| Online Access: | https://doi.org/10.1038/s41514-018-0029-z |