Morphological Subtypes of Tumor Spread Through Air Spaces in Non-Small Cell Lung Cancer: Prognostic Heterogeneity and Its Underlying Mechanism

Morphological Subtypes of Tumor Spread Through Air Spaces in Non-Small Cell Lung Cancer: Prognostic Heterogeneity and Its Underlying Mechanism

BackgroundTumor spread through air spaces (STAS) has three morphologic subtypes: single cells, micropapillary clusters, and solid nests. However, whether their respective clinical significance is similar remains unclear.MethodsWe retrospectively reviewed 803 patients with resected non-small cell lun...

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Bibliographic Details
Main Authors: Huikang Xie, Hang Su, Erjia Zhu, Chang Gu, Shengnan Zhao, Yunlang She, Yijiu Ren, Dong Xie, Hui Zheng, Chunyan Wu, Chenyang Dai, Chang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
spread through air spaces
spread through a knife surface
non-small cell lung cancer
prognosis
artifact
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.608353/full

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