Icariin Regulates Cellular Functions and Gene Expression of Osteoarthritis Patient-Derived Human Fibroblast-Like Synoviocytes

Icariin Regulates Cellular Functions and Gene Expression of Osteoarthritis Patient-Derived Human Fibroblast-Like Synoviocytes

Synovial inflammation plays an important role in the pathogenesis and progress of osteoarthritis (OA). There is an urgent need to find safe and effective drugs that can reduce the inflammation and regulate the pathogenesis of cytokines of the OA disease. Here, we investigated the effect of icariin,...

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Bibliographic Details
Main Authors: Lianhong Pan, Yonghui Zhang, Na Chen, Li Yang
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
icariin
osteoarthritis
OA–FLSs
anti-inflammation
MMP14
GRP78
Online Access:https://www.mdpi.com/1422-0067/18/12/2656

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