Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias

Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias

Automated serum kappa (κ) and lambda (λ) free light chain (FLC) immunoassay may be used as a rapid screening tool for multiple myeloma and other light chain diseases as it is more sensitive and robust than serum protein electrophoresis (SPE) and urine immunofixation electrophoresis (IFE). Serum FLC...

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Main Authors: Clementine YF Yap MT(ASCP), DLM(ASCP), Pey Wah Wong BSc, Tar Choon Aw FRCP (Edin), FRCPA
Format: Article
Language:English
Published: SAGE Publishing 2011-03-01
Series:Proceedings of Singapore Healthcare
Online Access:https://doi.org/10.1177/201010581102000111
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spelling doaj-560eb20fbd9848aaa4d588db4f8d3f092020-11-25T03:28:23ZengSAGE PublishingProceedings of Singapore Healthcare2010-10582059-23292011-03-012010.1177/201010581102000111Free Kappa and Lambda Light Chains in Plasma Cell DyscrasiasClementine YF Yap MT(ASCP), DLM(ASCP)Pey Wah Wong BScTar Choon Aw FRCP (Edin), FRCPAAutomated serum kappa (κ) and lambda (λ) free light chain (FLC) immunoassay may be used as a rapid screening tool for multiple myeloma and other light chain diseases as it is more sensitive and robust than serum protein electrophoresis (SPE) and urine immunofixation electrophoresis (IFE). Serum FLC enables earlier diagnosis and evaluation of tumour response to therapy. Serum FLC testing has been incorporated into an international guideline for all newly diagnosed plasma cell cancers for diagnosis, prognosis, monitoring and assessing treatment.https://doi.org/10.1177/201010581102000111
collection DOAJ
language English
format Article
sources DOAJ
author Clementine YF Yap MT(ASCP), DLM(ASCP)
Pey Wah Wong BSc
Tar Choon Aw FRCP (Edin), FRCPA
spellingShingle Clementine YF Yap MT(ASCP), DLM(ASCP)
Pey Wah Wong BSc
Tar Choon Aw FRCP (Edin), FRCPA
Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias
Proceedings of Singapore Healthcare
author_facet Clementine YF Yap MT(ASCP), DLM(ASCP)
Pey Wah Wong BSc
Tar Choon Aw FRCP (Edin), FRCPA
author_sort Clementine YF Yap MT(ASCP), DLM(ASCP)
title Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias
title_short Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias
title_full Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias
title_fullStr Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias
title_full_unstemmed Free Kappa and Lambda Light Chains in Plasma Cell Dyscrasias
title_sort free kappa and lambda light chains in plasma cell dyscrasias
publisher SAGE Publishing
series Proceedings of Singapore Healthcare
issn 2010-1058
2059-2329
publishDate 2011-03-01
description Automated serum kappa (κ) and lambda (λ) free light chain (FLC) immunoassay may be used as a rapid screening tool for multiple myeloma and other light chain diseases as it is more sensitive and robust than serum protein electrophoresis (SPE) and urine immunofixation electrophoresis (IFE). Serum FLC enables earlier diagnosis and evaluation of tumour response to therapy. Serum FLC testing has been incorporated into an international guideline for all newly diagnosed plasma cell cancers for diagnosis, prognosis, monitoring and assessing treatment.
url https://doi.org/10.1177/201010581102000111
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