| Summary: | Background/Aim. The most common materials implanted in the human organism are
suture materials that are classified on the basis of several criteria,
usually the origin, structure, and properties. The properties of suture
materials are related to its absorbability and non-absorbability. When using
resorbable materials it is of great importance to determine whether its
absorbability and tensile strength help wound healing in function of time.
Sutures themselves can become a source of inflammation, that may reduce or
compromise the potential of reparation and regeneration. The aim of this
experimental study on dogs was to ascertain whether the absorption rate and
the degree of local tissue reactions differ from information provided by the
manufacturers, whether there are differences between the applied suture
materials and which of the used suture materials have better effect on wound
healing. Methods. Experimental testing of the selected suture materials
basic characteristics was performed on 6 German Shepherd dogs, which, after
induction of general anesthesia, were made 3 identical incisions each in all
4 quadrants (left and right side of the upper and lower jaws), so that 12
horizontal incisions were formed, 10 mm long, 20-25 mm distant from one
another, on each animal. Randomly, incisions were stitched up in the
following order, starting from back to front: catgut, Dexon®, Vicryl-Rapid®.
The experiment was terminated by histopathological examination of tissue
samples, taken on postoperative day 3, 7, 14 and 21 in order to identify the
effect of healing and the degree of local reaction. Results. The obtained
results suggest that catgut has the highest absorption rate, while Dexon®
the lowest. Vicryl-Rapid® causes the lowest level of local reactions, while
Dexon® the highest. Conclusion. There is no ideal suture material because
various patient factors also influence the wound healing process.
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