Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut

Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut

Abstract Background In vector-borne diseases such as leishmaniasis, the sand fly midgut is considered to be an important site for vector-parasite interaction. Digestive enzymes including serine peptidases such as trypsin and chymotrypsin, which are secreted in the midgut are one of the obstacles for...

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Bibliographic Details
Main Authors: Sudha Verma, Sushmita Das, Abhishek Mandal, Md Yousuf Ansari, Sujata Kumari, Rani Mansuri, Ajay Kumar, Ruby Singh, Savita Saini, Kumar Abhishek, Vijay Kumar, Ganesh Chandra Sahoo, Pradeep Das
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Parasites & Vectors
Subjects:
Sand fly midgut
Trypsin
Chymotrypsin
Inhibitor of serine peptidases
Leishmaniasis
Online Access:http://link.springer.com/article/10.1186/s13071-017-2239-9

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