Reversal of advanced fibrosis after long-term ursodeoxycholic acid therapy in a patient with residual expression of MdR3

Introduction. Progressive familial intrahepatic cholestasis type 3 (PFIC-3) is a severe liver disorder associated with inherited dysfunction of multidrug resistance protein 3 (MDR3/ABCB4), which functions as a phospholipid floppase, translocating phosphatidylcholine from the inner to the outer hemil...

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Bibliographic Details
Main Authors: Bernardo Frider, Amalia Castillo, Raquel Gordo-Gilart, Andrés Bruno, Marcelo Amante, Luis Alvarez, Verónica Mathet
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119307719