Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways.
The ability of the pathogenic yeast Candida albicans to interconvert between budded and hyphal growth states, herein termed the budded-to-hyphal transition (BHT), is important for C. albicans development and virulence. The BHT is under the control of multiple cell signaling pathways that respond to...
Main Authors: | John Midkiff, Nathan Borochoff-Porte, Dylan White, Douglas I Johnson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21966518/?tool=EBI |
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