The Innate and Adaptive Immune System as Targets for Biologic Therapies in Inflammatory Bowel Disease

The Innate and Adaptive Immune System as Targets for Biologic Therapies in Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is an immune-mediated inflammatory condition causing inflammation of gastrointestinal and systemic cells, with an increasing prevalence worldwide. Many factors are known to trigger and maintain inflammation in IBD including the innate and adaptive immune systems, gen...

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Bibliographic Details
Main Authors: Grainne Holleran, Loris Lopetuso, Valentina Petito, Cristina Graziani, Gianluca Ianiro, Deirdre McNamara, Antonio Gasbarrini, Franco Scaldaferri
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:International Journal of Molecular Sciences
Subjects:
inflammatory bowel disease
innate immunity
adaptive immunity
molecular targets
biologic therapies
Anti-TNF
Anti-integrins
inflammatory cytokines
Online Access:https://www.mdpi.com/1422-0067/18/10/2020

Internet

https://www.mdpi.com/1422-0067/18/10/2020

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