Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt/mTOR Signaling

Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt/mTOR Signaling

Neuroligins (NLs) are a group of postsynaptic cell adhesion molecules that function in synaptogenesis and synaptic transmission. Genetic defects in neuroligin 3 (NL3), a member of the NL protein family, are associated with autism. Studies in rodents have revealed that mutations of NL3 gene lead to i...

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Bibliographic Details
Main Authors: Jing Xu, Yong-lan Du, Jing-wei Xu, Xiao-ge Hu, Lin-fan Gu, Xiu-mao Li, Ping-hong Hu, Tai-lin Liao, Qiang-qiang Xia, Qi Sun, Lei Shi, Jian-hong Luo, Jun Xia, Ziyi Wang, Junyu Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuroligin 3
Akt/mTOR
dendritic outgrowth
PTEN
MAGI-2
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00518/full

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