Design, Synthesis, and Anticancer Effect Studies of Iridium(III) Polypyridyl Complexes against SGC-7901 Cells

Design, Synthesis, and Anticancer Effect Studies of Iridium(III) Polypyridyl Complexes against SGC-7901 Cells

Three iridium(III) complexes ([Ir(Hppy)<sub>2</sub>(L)](PF<sub>6</sub>) (Hppy = 2-phenylpyridine, L = 5-nitrophenanthroline, NP), <b>1</b>; 5-nitro-6-amino-phenanthroline (NAP), <b>2</b>; and 5,6-diamino-phenanthroline (DAP) <b>3</b> were s...

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Bibliographic Details
Main Authors: Li-Xia Zhang, Yi-Ying Gu, Yang-Jie Wang, Lan Bai, Fan Du, Wen-Yao Zhang, Miao He, Yun-Jun Liu, Yan-Zhong Chen
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
iridium(III) complexes
antitumor activity
mitochondrial dysfunction
DNA damage
apoptosis
Online Access:https://www.mdpi.com/1420-3049/24/17/3129

Internet

https://www.mdpi.com/1420-3049/24/17/3129

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