Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization

<p>Abstract</p> <p>Background</p> <p>Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is a crucial step when comparing measurements from these arrays. Norm...

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Bibliographic Details
Main Authors: van Someren Eugene P, Mentink Anouk, Hulsman Marc, Dechering Koen J, de Boer Jan, Reinders Marcel JT
Format: Article
Language:English
Published: BMC 2010-03-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/156