LONG-TERM OUTCOMES IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME IN THE APPLICATION OF A PHARMACOINVASIVE APPROACH AND PRIMARY PERCUTANEOUS CORONARY INTERVENTION: RESULTS OF A TWO-YEAR FOLLOW-UP IN REAL CLINICAL PRACTICE CONDITIONS

• Main Authors: A. S. Shilova, N. A. Novikova, D. Yu. Shchekochikhin, A. L. Syrkin
• Format: Article
• Language: Russian
• Published: ABV-press 2016-03-01
• Series: Klinicist
• Subjects: acute coronary syndrome; thrombolysis; pharmacoinvasive approach; primary percutaneous intervention on coronary arteries; reperfusion therapy; long-term prognosis; st-segment elevation; combined policy
• Online Access: https://klinitsist.abvpress.ru/Klin/article/view/230

Objective: to assess and compare outcomes in patients with ST-segment elevation acute coronary syndrome (STEACS) during 28 months of follow-up in relation to reperfusion therapy policy.Materials and methods. The investigation was based on the hospital registry of patients with acute coronary syndrome. This investigation enrolled 259 patients with STEACS hospitalized through the emergency medical care channel from January 1, 2012 to January 1, 2013. The safety and efficiency of a pharmacoinvasive (PI) approach (n = 60) and primary percutaneous coronary intervention (PCI) (n = 91) were comparatively analyzed after 28 months of follow-up.Results. The choice of a reperfusion therapy option (primary PCI or PI approach) failed to affect survival in the patients during 28 months of follow-up. The prediction of cardiovascular mortality and morbidity did not differ in both groups in the study period.Conclusion. The application of the PI approach to treating patients with STEACS was comparable in its efficiency and impact on long-term outcome as compared to primary PCI in real Russian practice conditions.