Overexpression of kermit/dGIPC is associated with lethality in Drosophila melanogaster

Overexpression of kermit/dGIPC is associated with lethality in Drosophila melanogaster

Show other versions (1)

Insertional mutagenesis is an important tool for functional genomics in Drosophila melanogaster. The insertion site in the KG00562 mutant fly line has been mapped to the CG8709 (herein named DmLpin) locus and to the 3’ of kermit (also called dGIPC). This mutant line presents a high lethality rate re...

Full description

Bibliographic Details
Main Authors:	G.B. Pereira, V. Valente, M.S. de Queiroz, M.C.B. Vianna, M.L. Paçó-Larson
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2011-04-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Insertional mutagenesis Aberrant splicing DmLpin Kermit/dGIPC
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000400003&lng=en&tlng=en

Similar Items

Overexpression of kermit/dGIPC is associated with lethality in Drosophila melanogaster
by: G.B. Pereira, et al.
Published: (2011-04-01)

Strength and duration of GIPC-dependent signaling networks as determinants in cancer
by: Tasmia Ahmed, et al.
Published: (2021-02-01)

GIPC proteins negatively modulate Plexind1 signaling during vascular development
by: Jorge Carretero-Ortega, et al.
Published: (2019-05-01)

Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex
by: Guijun Shang, et al.
Published: (2017-05-01)

Molecular characterization and ligand binding specificity of the PDZ domain-containing protein GIPC3 from <it>Schistosoma japonicum</it>
by: Mu Yi, et al.
Published: (2012-10-01)

Genetic Variant c.245A>G (p.Asn82Ser) in <i>GIPC3</i> Gene Is a Frequent Cause of Hereditary Nonsyndromic Sensorineural Hearing Loss in Chuvash Population
by: Nika V. Petrova, et al.
Published: (2021-05-01)

Acute recurrent rhabdomyolysis in a Chinese boy associated with a novel compound heterozygous LPIN1 variant: a case report
by: Ke Tong, et al.
Published: (2021-01-01)

Identification of the transcript isoforms and expression characteristics for chicken Lpin1
by: X.K. Wang, et al.
Published: (2012-01-01)

Zeamide, a Glycosylinositol Phosphorylceramide with the Novel Core Arap(1β→6)Ins Motif from the Marine Sponge Svenzea zeai
by: Gerardo Della Sala, et al.
Published: (2017-09-01)

The influence of radio-mimetic chemical mutagen on the chromosomal complex of winter wheat cells
by: M. M. Nazarenko
Published: (2017-05-01)

Duration of the flaxseed diet promotes deposition of n-3 fatty acids in the meat and skin of Peking ducks
by: Muhammad Suhaib Shahid, et al.
Published: (2019-12-01)

Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes
by: Tamer Bego, et al.
Published: (2011-02-01)

LPIN1 - étude génétique d'une nouvelle cause de rhabdomyolyse héréditaire et analyses physiopathologiques à partir de myoblastes de patients
by: Michot, Caroline
Published: (2013)

The Arabidopsis thaliana nucleotide sugar transporter GONST2 is a functional homolog of GONST1
by: Beibei Jing, et al.
Published: (2021-03-01)

Chasing the Major Sphingolipids on Earth: Automated Annotation of Plant Glycosyl Inositol Phospho Ceramides by Glycolipidomics
by: Lisa Panzenboeck, et al.
Published: (2020-09-01)

IL-33-Induced Transcriptional Activation of LPIN1 Accelerates Breast Tumorigenesis
by: Jin-Young Kim, et al.
Published: (2021-04-01)

Effects of H2O2, Fe2+ and Fe3+ on curcumin-induced chromosomal aberrations in CHO cells
by: Lusânia Maria Greggi Antunes, et al.
Published: (2005-03-01)

LPIN1 deficiency with severe recurrent rhabdomyolysis and persistent elevation of creatine kinase levels due to chromosome 2 maternal isodisomy
by: I.A. Meijer, et al.
Published: (2015-12-01)

Genetic damage induced by trophic doses of lead in the neotropical fish Hoplias malabaricus (Characiformes, Erythrinidae) as revealed by the comet assay and chromosomal aberrations
by: Marta Margarete Cestari, et al.
Published: (2004-01-01)

The Tumor Suppressor TGFBR3 Blocks Lymph Node Metastasis in Head and Neck Cancer
by: Wei-Yu Fang, et al.
Published: (2020-05-01)

A rare case of pediatric recurrent rhabdomyolysis with compound heterogenous variants in the LPIN1
by: Ruochen Che, et al.
Published: (2020-05-01)

LPIN1 Induces Gefitinib Resistance in EGFR Inhibitor-Resistant Non-Small Cell Lung Cancer Cells
by: Cho, J.H, et al.
Published: (2022)

Chromosomal aberrations in peripheral lymphocytes from male native miners working in the Peruvian Andes
by: Sergio R. Santa Maria, et al.
Published: (2007-01-01)

Dihydropteridine Reductase
by: Whiteley John M., et al.
Published: (1993-11-01)

De novo Design of G Protein-Coupled Receptor 40 Peptide Agonists for Type 2 Diabetes Mellitus Based on Artificial Intelligence and Site-Directed Mutagenesis
by: Xu Chen, et al.
Published: (2021-06-01)

Majeed Syndrome: A Review of the Clinical, Genetic and Immunologic Features
by: Polly J. Ferguson, et al.
Published: (2021-02-01)

Variation in the Lipin 1 Gene Is Associated with Birth Weight and Selected Carcass Traits in New Zealand Romney Sheep
by: Guan Wang, et al.
Published: (2020-02-01)

"Increased Quality with Static Dollars," Kermit Morrissey
Published: ()

An implementation of the Kermit protocol using the Edison system
by: Scott, Terry A.
Published: (2011)

THE EFFECT OF TEMPERATURE ON THE EXPRESSION OF ENZYMES IN THE VESTIGIAL MUTANT OF DROSOPHILA MELANOGASTER
by: Pardy, Rosevelt L.
Published: (1969)

Assessment on cytotoxic and mutagenic potency of Gamma rays and EMS in Vigna mungo L. Hepper
by: Sonu Goyal, et al.
Published: (2019-09-01)

Mutagenesis at Five Pteridine Pathway Loci In Drosophila melanogaster: Genetic and Biochemical Characterization
by: Millán J.M., et al.
Published: (1993-08-01)

Kermit: linkage map guided long read assembly
by: Riku Walve, et al.
Published: (2019-03-01)

Pendidikan Kesehatan Tentang Diet Terhadap Kepatuhan Pasien Diabetes Mellitus
by: Suratun Haryono, et al.
Published: (2018-12-01)

miR-429-3p/LPIN1 Axis Promotes Chicken Abdominal Fat Deposition via PPARγ Pathway
by: Xiaohuan Chao, et al.
Published: (2020-12-01)

Function of the α/β-hydrolase fold family proteins Pummelig (CG1882) and Hormone-sensitive lipase in the Drosophila melanogaster lipid metabolism
by: Hehlert, Philip
Published: (2016)

Therapeutic implications of GIPC1 silencing in cancer.
by: Thomas W Chittenden, et al.
Published: (2010-12-01)

Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli
by: Toon Swings, et al.
Published: (2017-05-01)

Autosomal products of meiosis arising from radiation-induced interchange in female Drosophila Melanogaster
by: Gibson, William Glen
Published: (2010)

Glycemic control in children and adolescents with type 1 diabetes mellitus in post conflict Iraq: a primary report
by: Dena M. Kadhim, et al.
Published: (2016-10-01)