Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report

Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report

Abstract Background Glioblastoma (GBM) is a highly malignant brain neoplasm with poor survival. Despite its aggressive nature, metastatic spread of GBM is identified only rarely. While the molecular alterations associated with GBM and its subtypes are well-described, there remains a gap in understan...

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Bibliographic Details
Main Authors: Melissa Umphlett, Stephanie Shea, Jessica Tome-Garcia, Yizhou Zhang, Adilia Hormigo, Mary Fowkes, Nadejda M. Tsankova, Raymund L. Yong
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Cancer
Subjects:
Glioblastoma
Metastasis
BRCA1 mutation
ARID1A mutation
Mismatch repair deficiency
Temozolomide
Online Access:https://doi.org/10.1186/s12885-020-6540-1

Internet

https://doi.org/10.1186/s12885-020-6540-1

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