Measuring inorganic phosphate and intracellular pH in the healthy and hypertrophic cardiomyopathy hearts by in vivo 7T 31P-cardiovascular magnetic resonance spectroscopy

Measuring inorganic phosphate and intracellular pH in the healthy and hypertrophic cardiomyopathy hearts by in vivo 7T 31P-cardiovascular magnetic resonance spectroscopy

Abstract Background Cardiovascular phosphorus MR spectroscopy (31P-CMRS) is a powerful tool for probing energetics in the human heart, through quantification of phosphocreatine (PCr) to adenosine triphosphate (ATP) ratio. In principle, 31P-CMRS can also measure cardiac intracellular pH (pHi) and the...

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Bibliographic Details
Main Authors: Ladislav Valkovič, William T. Clarke, Albrecht I. Schmid, Betty Raman, Jane Ellis, Hugh Watkins, Matthew D. Robson, Stefan Neubauer, Christopher T. Rodgers
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Cardiovascular Magnetic Resonance
Subjects:
31P CMRS
7T
Cardiac intracellular pH
3D-CSI
Cardiac Pi
Online Access:http://link.springer.com/article/10.1186/s12968-019-0529-4

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