Trelagliptin succinate: DPP-4 inhibitor to improve insulin resistance in adipocytes

Trelagliptin inhibits the enzyme dipeptidyl-4 (DPP-4) to treat type 2 diabetes and it may possess the potential to improve insulin resistance. However, the molecular mechanism is not known. In this study, the effect of trelagliptin succinate in improving insulin resistance was investigated. The diff...

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Bibliographic Details
Main Authors: Zhenhua Liu, Lanting Xu, Meimei Xing, Xiaojie Xu, Jinfeng Wei, Jinmei Wang, Wenyi Kang
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301426