Neutrophil elastase as a biomarker for bacterial infection in COPD
Abstract Background Chronic obstructive pulmonary disease (COPD) is predominantly associated with neutrophilic inflammation. Active neutrophil elastase (NE) is a serine proteinase, secreted by neutrophils, in response to inflammation and pathogen invasion. We sought to investigate if NE could be use...
Main Authors: | Samantha J. Thulborn, Vijay Mistry, Christopher E. Brightling, Kelly L. Moffitt, David Ribeiro, Mona Bafadhel |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | Respiratory Research |
Online Access: | http://link.springer.com/article/10.1186/s12931-019-1145-4 |
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