Neutrophil elastase as a biomarker for bacterial infection in COPD

Abstract Background Chronic obstructive pulmonary disease (COPD) is predominantly associated with neutrophilic inflammation. Active neutrophil elastase (NE) is a serine proteinase, secreted by neutrophils, in response to inflammation and pathogen invasion. We sought to investigate if NE could be use...

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Bibliographic Details
Main Authors: Samantha J. Thulborn, Vijay Mistry, Christopher E. Brightling, Kelly L. Moffitt, David Ribeiro, Mona Bafadhel
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Respiratory Research
Online Access:http://link.springer.com/article/10.1186/s12931-019-1145-4

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