Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres

Radiation segmentectomy (RS) is a new approach to 90Y radioembolization that has been designed to increase the safety and efficacy of radioembolization in patients with unresectable hepatic malignancies. With this technique, high doses (>190 Gy) of radiation are delivered to the tumor through rad...

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Bibliographic Details
Main Authors: Zhongzhi Jia, Caoye Wang, Ricardo Paz-Fumagalli, Weiping Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-02-01
Series:Journal of Interventional Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2096360219300614
Description
Summary:Radiation segmentectomy (RS) is a new approach to 90Y radioembolization that has been designed to increase the safety and efficacy of radioembolization in patients with unresectable hepatic malignancies. With this technique, high doses (>190 Gy) of radiation are delivered to the tumor through radioembolization performed in a segmental fashion, potentially increasing the radiation dose to the tumor while minimizing injury to the liver parenchyma. The aim of this review is to provide a summary of the indications, device choice, dosimetry, procedure, clinical outcomes, and toxicity of RS based on the clinical series currently available. Keywords: Hepatic malignancy, Yttrium-90, Radioembolization, Radiation segmentectomy
ISSN:2096-3602