Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method

Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method

The radical-scavenging activities of the synthetic antioxidants 2-allyl-4-X-phenol (X=NO2, Cl, Br, OCH3, COCH3, CH3, t-(CH3)3, C6H5) and 2,4-dimethoxyphenol, and the natural antioxidants eugenol and isoeugenol, were investigated using differential scanning calorimetry (DSC) by measuring their anti-1...

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Main Authors: Ichiro Yokoe, Mariko Ishihara, Norihisa Okada, Toshiko Atsumi, Yoshinori Kadoma, Seiichiro Fujisawa
Format: Article
Language:English
Published: MDPI AG 2007-02-01
Series:Molecules
Subjects:
Radical-scavenging activity
natural and synthetic methoxyphenols
DPPH
BPO
AIBN
induction method.
Online Access:http://www.mdpi.com/1420-3049/12/2/130/
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spelling doaj-55831d6d0d8a4ab68dd2d5b3cc73b5612020-11-24T21:25:12ZengMDPI AGMolecules1420-30492007-02-0112213013810.3390/12020130Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period MethodIchiro YokoeMariko IshiharaNorihisa OkadaToshiko AtsumiYoshinori KadomaSeiichiro FujisawaThe radical-scavenging activities of the synthetic antioxidants 2-allyl-4-X-phenol (X=NO2, Cl, Br, OCH3, COCH3, CH3, t-(CH3)3, C6H5) and 2,4-dimethoxyphenol, and the natural antioxidants eugenol and isoeugenol, were investigated using differential scanning calorimetry (DSC) by measuring their anti-1,1-diphenyl-2-picrylhydrazyl (DPPH) radical activity and the induction period for polymerization of methyl methacrylate (MMA) initiated by thermal decomposition of 2,2'-azobisisobutyronitrile (AIBN) and benzoyl peroxide (BPO). 2-Allyl-4-methoxyphenol and 2,4-dimethoxy-phenol scavenged not only oxygen-centered radicals (PhCOO.) derived from BPO, but also carbon-centered radicals (R.) derived from the AIBN and DPPH radical much more efficiently, in comparison with eugenol and isoeugenol. 2-Allyl-4-methoxyphenol may be useful for its lower prooxidative activity. http://www.mdpi.com/1420-3049/12/2/130/Radical-scavenging activitynatural and synthetic methoxyphenolsDPPHBPOAIBNinduction method.
collection DOAJ
language English
format Article
sources DOAJ
author Ichiro Yokoe
Mariko Ishihara
Norihisa Okada
Toshiko Atsumi
Yoshinori Kadoma
Seiichiro Fujisawa
spellingShingle Ichiro Yokoe
Mariko Ishihara
Norihisa Okada
Toshiko Atsumi
Yoshinori Kadoma
Seiichiro Fujisawa
Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method
Molecules
Radical-scavenging activity
natural and synthetic methoxyphenols
DPPH
BPO
AIBN
induction method.
author_facet Ichiro Yokoe
Mariko Ishihara
Norihisa Okada
Toshiko Atsumi
Yoshinori Kadoma
Seiichiro Fujisawa
author_sort Ichiro Yokoe
title Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method
title_short Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method
title_full Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method
title_fullStr Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method
title_full_unstemmed Radical-scavenging Activity of Natural Methoxyphenols vs. Synthetic Ones using the Induction Period Method
title_sort radical-scavenging activity of natural methoxyphenols vs. synthetic ones using the induction period method
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2007-02-01
description The radical-scavenging activities of the synthetic antioxidants 2-allyl-4-X-phenol (X=NO2, Cl, Br, OCH3, COCH3, CH3, t-(CH3)3, C6H5) and 2,4-dimethoxyphenol, and the natural antioxidants eugenol and isoeugenol, were investigated using differential scanning calorimetry (DSC) by measuring their anti-1,1-diphenyl-2-picrylhydrazyl (DPPH) radical activity and the induction period for polymerization of methyl methacrylate (MMA) initiated by thermal decomposition of 2,2'-azobisisobutyronitrile (AIBN) and benzoyl peroxide (BPO). 2-Allyl-4-methoxyphenol and 2,4-dimethoxy-phenol scavenged not only oxygen-centered radicals (PhCOO.) derived from BPO, but also carbon-centered radicals (R.) derived from the AIBN and DPPH radical much more efficiently, in comparison with eugenol and isoeugenol. 2-Allyl-4-methoxyphenol may be useful for its lower prooxidative activity.
topic Radical-scavenging activity
natural and synthetic methoxyphenols
DPPH
BPO
AIBN
induction method.
url http://www.mdpi.com/1420-3049/12/2/130/
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AT marikoishihara radicalscavengingactivityofnaturalmethoxyphenolsvssyntheticonesusingtheinductionperiodmethod
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AT yoshinorikadoma radicalscavengingactivityofnaturalmethoxyphenolsvssyntheticonesusingtheinductionperiodmethod
AT seiichirofujisawa radicalscavengingactivityofnaturalmethoxyphenolsvssyntheticonesusingtheinductionperiodmethod
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