Examination of the roles of a conserved motif in the PriA helicase in structure-specific DNA unwinding and processivity.

DNA replication complexes (replisomes) frequently encounter barriers that can eject them prematurely from the genome. To avoid the lethality of incomplete DNA replication that arises from these events, bacteria have evolved "DNA replication restart" mechanisms to reload replisomes onto aba...

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Bibliographic Details
Main Authors: Alexander T Duckworth, Tricia A Windgassen, James L Keck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0255409