PPS, a large multidomain protein, functions with sex-lethal to regulate alternative splicing in Drosophila.
Alternative splicing controls the expression of many genes, including the Drosophila sex determination gene Sex-lethal (Sxl). Sxl expression is controlled via a negative regulatory mechanism where inclusion of the translation-terminating male exon is blocked in females. Previous studies have shown t...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-03-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2832672?pdf=render |