MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma

MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma

Abstract Background LncRNA NEAT1 has been identified as a tumour driver in many human cancers. However, the underlying mechanism of lncRNA NEAT1 in diffuse large B-cell lymphoma (DLBCL) progression is unclear. Methods The expression levels of NEAT1, GLI1 and miR-34b-5p were detected by RT-qPCR and W...

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Bibliographic Details
Main Authors: Chong-Sheng Qian, Ling-Jie Li, Hai-Wen Huang, Hai-Fei Yang, De-Pei Wu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cancer Cell International
Subjects:
Cell proliferation
Diffuse large B-cell lymphoma
GLI1
MYC
LncRNA NEAT1
Online Access:http://link.springer.com/article/10.1186/s12935-020-1158-6

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http://link.springer.com/article/10.1186/s12935-020-1158-6

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