The Functional Classification of ORF8 in SARS-CoV-2 Replication, Immune Evasion, and Viral Pathogenesis Inferred through Phylogenetic Profiling

The Functional Classification of ORF8 in SARS-CoV-2 Replication, Immune Evasion, and Viral Pathogenesis Inferred through Phylogenetic Profiling

ORF8 is a highly variable genomic region of SARS-CoV-2. Although non-essential and the precise functions are unknown, it has been suggested that this protein assists in SARS-CoV-2 replication in the early secretory pathway and in immune evasion. We utilized the binding partners of SARS-CoV-2 protein...

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Bibliographic Details
Main Authors: Muhamad Fahmi, Hiromu Kitagawa, Gen Yasui, Yukihiko Kubota, Masahiro Ito
Format: Article
Language:English
Published: SAGE Publishing 2021-03-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.1177/11769343211003079

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