Conditioned Medium from Malignant Breast Cancer Cells Induces an EMT-Like Phenotype and an Altered N-Glycan Profile in Normal Epithelial MCF10A Cells

Conditioned Medium from Malignant Breast Cancer Cells Induces an EMT-Like Phenotype and an Altered N-Glycan Profile in Normal Epithelial MCF10A Cells

Epithelial-mesenchymal transition (EMT) is a key process in cancer development and progression. Communication (crosstalk) between cancer cells and normal (nonmalignant) cells may facilitate cancer progression. Conditioned medium (CM) obtained from cultured cancer cells contains secreted factors capa...

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Bibliographic Details
Main Authors: Jia Guo, Changmei Liu, Xiaoman Zhou, Xiaoqiang Xu, Linhong Deng, Xiang Li, Feng Guan
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:International Journal of Molecular Sciences
Subjects:
conditioned medium
EMT
N-glycan
breast cancer
cell migration
Online Access:https://www.mdpi.com/1422-0067/18/8/1528

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