Impact of mTOR signaling pathway on CD8+ T cell immunity through Eomesodermin in response to invasive candidiasis

Impact of mTOR signaling pathway on CD8+ T cell immunity through Eomesodermin in response to invasive candidiasis

Background: We investigated the effect of the mammalian target of rapamycin (mTOR) pathway on CD8+ T cell immunity through Eomesodermin (Eomes) in intensive care unit (ICU) patients with invasive candidiasis (IC) and in a mouse model. Methods: We evaluated quantitative changes in parameters of the m...

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Bibliographic Details
Main Authors: Jiahui Zhang, Na Cui, Hao Wang, Wen Han, Guangxu Bai, Wei Cheng
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
CD8+ T cells
Eomesodermin
Invasive candidiasis
Mammalian target of rapamycin
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118221000906

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