Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer.

Breast cancers can recur after removal of the primary tumor and treatment to eliminate remaining tumor cells. Recurrence may occur after long periods of time during which there are no clinical symptoms. Tumor cell dormancy may explain these prolonged periods of asymptomatic residual disease and trea...

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Bibliographic Details
Main Authors: Ryung S Kim, Alvaro Avivar-Valderas, Yeriel Estrada, Paloma Bragado, Maria Soledad Sosa, Julio A Aguirre-Ghiso, Jeffrey E Segall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329481?pdf=render