A MAGEL2-deubiquitinase complex modulates the ubiquitination of circadian rhythm protein CRY1.

A MAGEL2-deubiquitinase complex modulates the ubiquitination of circadian rhythm protein CRY1.

MAGEL2 encodes the L2 member of the MAGE (melanoma antigen) protein family. Protein truncating mutations in MAGEL2 cause Schaaf-Yang syndrome, and MAGEL2 is one of a small set of genes deleted in Prader-Willi syndrome. Excessive daytime sleepiness, night-time or early morning waking, and narcoleptic...

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Bibliographic Details
Main Authors: K Vanessa Carias, Mercedes Zoeteman, Abigail Seewald, Matthea R Sanderson, Jocelyn M Bischof, Rachel Wevrick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230874

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