Lactobacillus rhamnosus GG strain mitigated the development of obstructive sleep apnea-induced hypertension in a high salt diet via regulating TMAO level and CD4+ T cell induced-type I inflammation

Lactobacillus rhamnosus GG strain mitigated the development of obstructive sleep apnea-induced hypertension in a high salt diet via regulating TMAO level and CD4+ T cell induced-type I inflammation

Obstructive sleep apnea (OSA) and high salt content in modern diet has been particularly implicated in systemic hypertension, leading to increased morbidity and mortality. Gut dysbiosis, associated with increased risk of systemic immunological imbalance, plays a causal role in the development of car...

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Bibliographic Details
Main Authors: Jing Liu, Tianxiang Li, Hui Wu, Haoze Shi, Jinmei Bai, Wei Zhao, Donghui Jiang, Xiufeng Jiang
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Hypertension
Chronic intermittent hypoxia
High salt diet
Microbiota
Immune system
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218383537

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