Obesity Promotes EAE Through IL-6 and CCL-2-Mediated T Cells Infiltration

Obesity Promotes EAE Through IL-6 and CCL-2-Mediated T Cells Infiltration

Growing evidence suggests that obesity is associated with the susceptibility and disease severity of multiple sclerosis. The chronic inflammation induced by obesity is believed to contribute to this process. However, the immune mechanisms connecting obesity to the prevalence and pathogenesis of MS a...

Full description

Bibliographic Details
Main Authors: Zhe Ji, Shuai Wu, Yaru Xu, Jingjing Qi, Xiaohui Su, Lei Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
obesity
EAE
infiltration of T lymphocyte
CCL-2
IL-6
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01881/full

Similar Items

Similar Items