Ethical issues in pragmatic randomized controlled trials: a review of the recent literature identifies gaps in ethical argumentation

Ethical issues in pragmatic randomized controlled trials: a review of the recent literature identifies gaps in ethical argumentation

Abstract Background Pragmatic randomized controlled trials (RCTs) are designed to evaluate the effectiveness of interventions in real-world clinical conditions. However, these studies raise ethical issues for researchers and regulators. Our objective is to identify a list of key ethical issues in pr...

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Bibliographic Details
Main Authors: Cory E. Goldstein, Charles Weijer, Jamie C. Brehaut, Dean A. Fergusson, Jeremy M. Grimshaw, Austin R. Horn, Monica Taljaard
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Medical Ethics
Subjects:
Pragmatic randomized controlled trials
Literature review
Ethics
Informed consent
Disclosure
Oversight
Online Access:http://link.springer.com/article/10.1186/s12910-018-0253-x

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