In Vitro Neuroprotection of Rat Hippocampal Neurons by Manninotriose and Astragaloside IV Against Corticosterone-Induced Toxicity

In Vitro Neuroprotection of Rat Hippocampal Neurons by Manninotriose and Astragaloside IV Against Corticosterone-Induced Toxicity

A chronically elevated glucocorticoid level impairs memory and cognition. Manninotriose is the main oligosaccharide of Prepared Radix Rehmanniae, and Astragaloside IV (AS-IV) is the primary ingredient of Astragali Radix; they have been reported to possess neuroprotective effects. The aim of the pres...

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Bibliographic Details
Main Authors: Jing Zheng, Fang Yin, Guoqin Jin, Xueli Zhang, Lina Zhang, Zhangbin Gong, Xiangping Kang, Haiyan Hu
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
corticosterone
Manninotriose
Astragaloside IV
learning and memory relevant genes
DNA methylation
Online Access:https://www.mdpi.com/1420-3049/23/12/3339

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