Assessment of Amyloid Deposition in Patients With Probable REM Sleep Behavior Disorder as a Prodromal Symptom of Dementia With Lewy Bodies Using PiB-PET

Assessment of Amyloid Deposition in Patients With Probable REM Sleep Behavior Disorder as a Prodromal Symptom of Dementia With Lewy Bodies Using PiB-PET

Introduction: Dementia with Lewy bodies (DLB) often exhibits REM sleep behavior disorder (RBD) at its prodromal stage. Meanwhile, DLB is often comorbid with Alzheimer's disease (AD)-type pathology. In typical AD, amyloid-β deposition begins considerably before the onset of dementia and has alre...

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Bibliographic Details
Main Authors: Ryota Kobayashi, Hiroshi Hayashi, Shinobu Kawakatsu, Nobuyuki Okamura, Masanori Yoshioka, Koichi Otani
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neurology
Subjects:
Dementia with Lewy bodies
REM sleep behavior disorder
Alzheimer's disease
amyloid-β
prodromal stage
PiB-PET
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00671/full

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