Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice

Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice

Sex differences in the brain have prompted many researchers to investigate the underlying molecular actors, such as the glucocorticoid receptor (GR). This nuclear receptor controls gene expression, including microRNAs (miRNAs), in non-neuronal cells. Here, we investigated sex-biased effects of GR on...

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Bibliographic Details
Main Authors: Macarena Tejos-Bravo, Robert H. Oakley, Shannon D. Whirledge, Wladimir A. Corrales, Juan P. Silva, Gonzalo García-Rojo, Jorge Toledo, Wendy Sanchez, Luciano Román-Albasini, Esteban Aliaga, Felipe Aguayo, Felipe Olave, Vinicius Maracaja-Coutinho, John A. Cidlowski, Jenny L. Fiedler
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Neurobiology of Stress
Subjects:
Glucocorticoid receptor
Hippocampus
miRNAs
Neuroplasticity
Dendrites
Dendritic spines
Online Access:http://www.sciencedirect.com/science/article/pii/S235228952100014X

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