Inhibitory effect of isoliquiritigenin isolated from Glycyrrhizae Radix on amyloid-β production in Swedish mutant amyloid precursor protein-transfected Neuro2a cells

Alzheimer's disease (AD) is a form of dementia, and its pathological characteristics involve the accumulation of amyloid-β (Aβ) produced by the cleavage of amyloid precursor protein (APP). According to the amyloidogenic pathway, Aβ is generated by the initial action of the β-site APP cleaving e...

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Bibliographic Details
Main Authors: Eun-Ju Yang, Geum-Sook Kim, Hyungjun Noh, Yu-Su Shin, Kyung-Sik Song
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615003849