Ibuprofen Inhibits Colitis-Induced Overexpression of TumorRelated Rac1b
The serrated pathway to colorectal tumor formation involves oncogenic mutations in the BRAF gene, which are sufficient for initiation of hyperplastic growth but not for tumor progression. A previous analysis of colorectal tumors revealed that overexpression of splice variant Rac1b occurs in around...
Main Authors: | Paulo Matos, Larissa Kotelevets, Peter Jordan, Vânia Gonçalves, Andreia Henriques, Philippe Zerbib, Mary Pat Moyer, Eric Chastre |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-01-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558613801303 |
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