α-amyrin-loaded nanocapsules produce selective cytotoxic activity in leukemic cells

Introduction: Amyrins are triterpenes that have attractive pharmacological potential; however, their low water solubility and erratic stomach absorption hinders their use as a drug. The aim of this paper was to develop a novel α-amyrin-loaded nanocapsule for intestinal delivery and evaluate, prelimi...

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Bibliographic Details
Main Authors: Serafim Florentino Neto, Ariadna Lafourcade Prada, Leonardo Domingo Rosales Achod, Heron Fernandes Vieira Torquato, Cauê Santos Lima, Edgar Julian Paredes-Gamero, Maria Oneide Silva de Moraes, Emerson Silva Lima, Edgar Hernandez Sosa, Tatiane Pereira de Souza, Jesus Rafael Rodriguez Amado
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221004388