Cofilin oligomer formation occurs in vivo and is regulated by cofilin phosphorylation.

Cofilin oligomer formation occurs in vivo and is regulated by cofilin phosphorylation.

BACKGROUND: ADF/cofilin proteins are key regulators of actin dynamics. Their function is inhibited by LIMK-mediated phosphorylation at Ser-3. Previous in vitro studies have shown that dependent on its concentration, cofilin either depolymerizes F-actin (at low cofilin concentrations) or promotes act...

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Bibliographic Details
Main Authors: Pankaj Goyal, Dharmendra Pandey, Daniela Brünnert, Elke Hammer, Marek Zygmunt, Wolfgang Siess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3738525?pdf=render

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