Acute regulation of 5′-AMP-activated protein kinase by long-chain fatty acid, glucose and insulin in rat primary adipocytes

Palmitate increased AMPK (5′-AMP-activated protein kinase) activity, glucose utilization and 2-DOG (2-deoxyglucose) transport in rat adipocytes. All three effects were blocked by the AMPK inhibitor Compound C, leading to the conclusion that in response to an increase in long-chain NEFA (n...

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Bibliographic Details
Main Authors: Abdel Hebbachi, David Saggerson
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2012-12-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/033/e007/bsr033e007.htm