Acute regulation of 5′-AMP-activated protein kinase by long-chain fatty acid, glucose and insulin in rat primary adipocytes
Palmitate increased AMPK (5′-AMP-activated protein kinase) activity, glucose utilization and 2-DOG (2-deoxyglucose) transport in rat adipocytes. All three effects were blocked by the AMPK inhibitor Compound C, leading to the conclusion that in response to an increase in long-chain NEFA (n...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Portland Press, Biochemical Society
2012-12-01
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Series: | Bioscience Reports |
Subjects: | |
Online Access: | http://www.bioscirep.org/bsr/033/e007/bsr033e007.htm |