CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portuguese center
Background: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well recognized. Objective: To investigate the p...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2012-04-01
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| Series: | Revista Portuguesa de Cardiologia |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0870255112000340 |
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by Rogério Teixeira, Pedro Monteiro, Gilberto Marques, João Pego, Margarida Lourenço, Carlos Tavares, Alda Reboredo, Sílvia Monteiro, Francisco Gonçalves, Maria J. Ferreira, Mário Freitas, Graça Ribeiro, Luís A. Providência
Published 2012-04-01
Get full textPublished 2012-04-01
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