HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression
Abstract Background Acute myeloid leukemia (AML) is recognized as a hematological neoplasm with heterogenetic cytology and short-term outcome. HCP5 has been proven to be related with the pathogenesis of AML. However, the underlying mechanism of HCP5 in AML remains unclear. Methods Clinical profiles...
Main Authors: | Yan Liu, Xue-Bing Jing, Zhen-Cheng Wang, Qing-Kun Han |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Human Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40246-021-00340-5 |
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