HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression

Abstract Background Acute myeloid leukemia (AML) is recognized as a hematological neoplasm with heterogenetic cytology and short-term outcome. HCP5 has been proven to be related with the pathogenesis of AML. However, the underlying mechanism of HCP5 in AML remains unclear. Methods Clinical profiles...

Full description

Bibliographic Details
Main Authors: Yan Liu, Xue-Bing Jing, Zhen-Cheng Wang, Qing-Kun Han
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-021-00340-5