mRNA Processing: An Emerging Frontier in the Regulation of Pancreatic β Cell Function
Robust endocrine cell function, particularly β cell function, is required to maintain blood glucose homeostasis. Diabetes can result from the loss or dysfunction of β cells. Despite decades of clinical and basic research, the precise regulation of β cell function and pathogenesis in diabetes remains...
Main Authors: | Nicole D. Moss, Lori Sussel |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-09-01
|
Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fgene.2020.00983/full |
Similar Items
-
Long Non-Coding RNAs as Key Modulators of Pancreatic β-Cell Mass and Function
by: Livia López–Noriega, et al.
Published: (2021-02-01) -
Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell loss
by: Daniel Oropeza, et al.
Published: (2021-08-01) -
miR-320a induces pancreatic β cells dysfunction in diabetes by inhibiting MafF
by: Hengzhi Du, et al.
Published: (2021-12-01) -
Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
by: Angela J Churchill, et al.
Published: (2017-01-01) -
Circular RNAs as Novel Regulators of β-Cell Functions under Physiological and Pathological Conditions
by: Flora Brozzi, et al.
Published: (2021-02-01)