Epoxyeicosatrienoic Acids and/or Their Metabolites Promote Hypoxic Response of Cells

Epoxyeicosatrienoic acids (EETs), including 5,6-EET, 8,9-EET, 11,12-EET, and 14,15-EET, are produced by cytochrome P450 (P450) such as CYP2C8 and 2C9; and they are hydrolyzed to dihydroxyeicosatrienoic acids (DHETs) by epoxide hydrolase. Particular interest in the epoxygenase reaction has developed...

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Bibliographic Details
Main Authors: Sachiko Suzuki, Ami Oguro, Mayuko Osada-Oka, Yoshihiko Funae, Susumu Imaoka
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319313775

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