Epoxyeicosatrienoic Acids and/or Their Metabolites Promote Hypoxic Response of Cells
Epoxyeicosatrienoic acids (EETs), including 5,6-EET, 8,9-EET, 11,12-EET, and 14,15-EET, are produced by cytochrome P450 (P450) such as CYP2C8 and 2C9; and they are hydrolyzed to dihydroxyeicosatrienoic acids (DHETs) by epoxide hydrolase. Particular interest in the epoxygenase reaction has developed...
Main Authors: | Sachiko Suzuki, Ami Oguro, Mayuko Osada-Oka, Yoshihiko Funae, Susumu Imaoka |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319313775 |
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